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  <xs:element id="tw_AdjustedForRefinitivTransactionMember" abstract="true" name="AdjustedForRefinitivTransactionMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_ChangeInContractWithCustomerLiabilityRollForward" abstract="true" name="ChangeInContractWithCustomerLiabilityRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="tw_NumberOfShareOwned" abstract="false" name="NumberOfShareOwned" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="tw_RegulatoryCapitalRequirement" abstract="false" name="RegulatoryCapitalRequirement" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="tw_RegulatoryCapitalRequirementsTextBlock" abstract="false" name="RegulatoryCapitalRequirementsTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="tw_TradewebMarketsIncMember" abstract="true" name="TradewebMarketsIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_RefinitivMember" abstract="true" name="RefinitivMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_ContractWithCustomerLiabilityNewBillings" abstract="false" name="ContractWithCustomerLiabilityNewBillings" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="tw_WholesaleClientSectorMember" abstract="true" name="WholesaleClientSectorMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_MarketDataClientSectorMember" abstract="true" name="MarketDataClientSectorMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_ShareBasedPaymentArrangementMultiplierAchievedAdjustmentIncreaseDecrease" abstract="false" name="ShareBasedPaymentArrangementMultiplierAchievedAdjustmentIncreaseDecrease" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="tw_DealerwebMember" abstract="true" name="DealerwebMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_TransactionFeeRevenueMember" abstract="true" name="TransactionFeeRevenueMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_TWMLLCMember" abstract="true" name="TWMLLCMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_MinorityInterestIncreaseDecreaseFromAdjustments" abstract="false" name="MinorityInterestIncreaseDecreaseFromAdjustments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="tw_RefinitivDirectOwnerMember" abstract="true" name="RefinitivDirectOwnerMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_EquitySettledPerformanceBasedRestrictedStockUnitsMember" abstract="true" name="EquitySettledPerformanceBasedRestrictedStockUnitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_ShareBasedCompensationArrangementByShareBasedPaymentAwardMaximumPerformanceModifier" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardMaximumPerformanceModifier" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="tw_ExecutionAccessMember" abstract="true" name="ExecutionAccessMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_ContractWithCustomerLiabilityForeignCurrencyExchangeRate" abstract="false" name="ContractWithCustomerLiabilityForeignCurrencyExchangeRate" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="tw_NoncashFinancingActivitiesOther" abstract="false" name="NoncashFinancingActivitiesOther" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="tw_Omnibus2019EquityIncentivePlanMember" abstract="true" name="Omnibus2019EquityIncentivePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" abstract="false" name="LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="tw_ShareBasedPaymentArrangementMultiplierAchievedPercent" abstract="false" name="ShareBasedPaymentArrangementMultiplierAchievedPercent" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="tw_TaxReceivableAgreementLiabilityAdjustment" abstract="false" name="TaxReceivableAgreementLiabilityAdjustment" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="tw_PublicInvestorsMember" abstract="true" name="PublicInvestorsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_RequiredLiquidFinancialAssets" abstract="false" name="RequiredLiquidFinancialAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="tw_ScheduleOfRegulatoryCapitalRequirementsTableTextBlock" abstract="false" name="ScheduleOfRegulatoryCapitalRequirementsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="tw_TaxReceivableAgreementLiability" abstract="false" name="TaxReceivableAgreementLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="tw_NetIncomeAttributableToParentAndTransfersToFromNoncontrollingInterest" abstract="false" name="NetIncomeAttributableToParentAndTransfersToFromNoncontrollingInterest" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="tw_TradewebJapanKkMember" abstract="true" name="TradewebJapanKkMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_TwSefLlcMember" abstract="true" name="TwSefLlcMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_VariablePricingMember" abstract="true" name="VariablePricingMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="tw_ParticipatingSecuritiesDistributedAndUndistributedEarningsLossShares" abstract="false" name="ParticipatingSecuritiesDistributedAndUndistributedEarningsLossShares" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
</xs:schema>
